FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\brnpr-fs
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General Information
Symbol
Dmel\brnpr-fs
Species
D. melanogaster
Name
FlyBase ID
FBal0013162
Feature type
allele
Associated gene
Dmel\br
Associated Insertion(s)
gypsy{}brnpr-fs
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
PM hybrid dysgenesis
(Orr et al., 1989)
Progenitor genotype
Associated Insertion(s)
gypsy{}brnpr-fs
Cytology
Description

gypsy element insertion.

(Huang and Orr, 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
S55610
S55612
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Females produce 'appendageless' eggs.

      (Deng and Bownes, 1997)

      In stage 13 of oogenesis nurse cell domain distension fails and subsequent readsorption of nurse cells produces a typical appendageless egg. Chorion gene amplification is abnormally arrested in stage 13 and 14 brnpr-fs follicles. Mosaic experiments reveal a somatic but not germ line requirement for 'npr' function.

      (Huang and Orr, 1992)

      Mature follicles of homozygous females have minor defects in the endochorion (which are uniformly distributed) and have defective respiratory appendages.

      (Orr et al., 1989)

      Morphologically abnormal eggs that fail to hatch. Various defects in respiratory appendages and chorionic architecture.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Germ line clonal analysis shows that fs(1)de1f is soma-dependent.

      (Orr et al., 1989)
      External Crossreferences and Linkouts ( 2 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      brde12
      brnpr-fs
      de12
      (Orr et al., 1989)
      fs(1)de12
      (Huang and Orr, 1992)
      nprfs
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0001225
      References (3)