FlyBase Allele Report: Dmel\olfA[x1]

General Information

Symbol

Dmel\olfA^x1

Species

D. melanogaster

Name

FlyBase ID

FBal0013238

Feature type

allele

Associated gene

olfA

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal smell perception | recessive

(Ayyub et al., 1990)

fertile

(Ayyub et al., 1990)

viable

(Ayyub et al., 1990)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygous adults show a partial reduction in their response to benzaldehyde in olfactory tests. Homozygous larvae do not show a significant change in the threshold of benzaldehyde detection, but there is an 80% reduction in maximal response compared to wild-type. Homozygous adults show a decreased response to salicylaldehyde and formaldehyde, while responses to ethyl acetate, acetone, acetic acid and ethanol are normal.

(Ayyub et al., 1990)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions