FB2026_03 , released September 17, 2026
Allele: Dmel\ome1
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General Information
Symbol
Dmel\ome1
Species
D. melanogaster
Name
omega
FlyBase ID
FBal0013255
Feature type
allele
Associated gene
Dmel\ome
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Chihara and Kimbrell, 1986)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G?C.

(Chihara et al., 2005)

Nucleotide substitution: G?A.

(Chihara et al., 2005)

Amino acid replacement: V?L.

(Chihara et al., 2005)

Amino acid replacement: W?term.

(Chihara et al., 2005)

The V?L change is in exon 3 and the termination codon mutation is in exon 4.

(Chihara et al., 2005)

Recessive allele. Lcp65Ab1/Lcp65Ab2 protein migrates more slowly in homozygotes, irrespective of the Lcp65Ab1/Lcp65Ab2 alleles present.

(Chihara and Kimbrell, 1986)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:14,744,261..14,744,261 [+]
Nucleotide change:

G14744261C

Reported nucleotide change:

G?C

Amino acid change:

V162L | ome-PE; V41L | ome-PF; V279L | ome-PG; V23L | ome-PH

Reported amino acid change:

V?L

Comment:

GB:AY245166 shows sequence of exon 3 in ome1 strain. One of 2 mutations in this line.

(Chihara et al., 2005)
point_mutation
3L:14,744,766..14,744,766 [+]
Nucleotide change:

G14744766A

Reported nucleotide change:

G?A

Amino acid change:

W301term | ome-PE; W180term | ome-PF; W418term | ome-PG; W162term | ome-PH

Reported amino acid change:

W?term

Comment:

GB:AY245167 shows sequence of exon 4 in ome1 strain. One of 2 mutations in this line; TGG to TAG

(Chihara et al., 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ome1 adults are 15-20% smaller than wild-type adults but there is no reduction in the size of ome1 eggs, third instar larvae or pupae. ome1 males show a decreased ability to fertilize females; the amount of progeny from females fertilized by ome1 males is also decreased.

      (Chihara et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ome1
      Name Synonyms
      omega
      (Chihara and Kimbrell, 1986)
      Secondary FlyBase IDs
        References (2)