FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pb31
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General Information
Symbol
Dmel\pb31
Species
D. melanogaster
Name
FlyBase ID
FBal0013535
Feature type
allele
Associated gene
Dmel\pb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Lewis et al., 1980)
Progenitor genotype
Cytology

Polytene chromosomes normal.

Description

Amino acid replacement: P701H.

(Tayyab et al., 2004)

Nucleotide substitution: C2102A.

(Tayyab et al., 2004)

The mutant allele contains the nucleotide polymorphism C2102A, which results in a P701H protein polymorphism (coordinates of the lesion are the position in the 2-μ-4a spliced form of pb).

(Tayyab et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The labial palp is transformed to antenna at 22oC and prothoracic leg at 29oC.

      (Cribbs et al., 1992)

      Transformation of labial palps to antenna or leg identity and an increase in number of bristles on the prementum.

      (Lewis et al., 1980)

      18oC --> leg 29oC --> antenna

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wakimoto.

      Comments
      Comments

      Behaves as a hypomorph at 22oC and an amorph at 29oC.

      (Cribbs et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      EfW4
      (Lewis et al., 1980)
      pb31
      (Tayyab et al., 2004)
      pbW4
      (Lewis et al., 1980)
      pbw4
      w4
      (Cribbs et al., 1992)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)