FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pb40
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General Information
Symbol
Dmel\pb40
Species
D. melanogaster
Name
FlyBase ID
FBal0013544
Feature type
allele
Associated gene
Dmel\pb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Cribbs et al., 1992)
Mutagen
X ray
Progenitor genotype
Cytology

Polytene chromosomes normal.

Description

Deletion of nucleotides 1767-1776. This results in a frameshift at amino acid residue 588, which produces a stop codon at residue 601 (coordinates of the lesions are the position in the 2-μ-4a spliced form of pb)

(Tayyab et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      pb40/pb20 flies have vestigial maxillary palps, the labellar caps are weakly transformed to tarsi (claws and pulvilli form, but the tarsi are short and stumpy and sometimes arista-like structures are observed) and the number of pseudotracheal rows is reduced to 0 to 1.

      (Tayyab et al., 2004)

      The labial palp is transformed to prothoracic leg.

      (Cribbs et al., 1992)

      leg

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Matthews.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pb40
      (Tayyab et al., 2004)
      pbx4
      x4
      (Cribbs et al., 1992)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)