FB2026_03 , released September 17, 2026
Allele: Dmel\phr1
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General Information
Symbol
Dmel\phr1
Species
D. melanogaster
Name
FlyBase ID
FBal0013792
Feature type
allele
Associated gene
Dmel\phr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Boyd and Harris, 1985)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutations exhibit a partial deficiency in the capacity to excise UV-induced pyrimidine dimers. In addition cells are defective in photorepair (FBrf0046353).

      (Todo and Ryo, 1992)

      Cells derived from homozygous embryos are totally incapable of photorepair (light induced reversal of pyrimidine dimers) and partially deficient in excision repair.

      (Boyd and Harris, 1987)

      Cells derived from homozygous embryos are deficient in photorepair: incapable of repairing UV-induced pyrimidine dimers after exposure to fluorescent illumination. Also there are some problems with excision repair. Since phr/phr larvae show little or no photoreactivation after exposure to short wavelength UV light, the phr+ function is thought to play a significant role in UV resistance.

      (Boyd and Harris, 1985)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Isolated from: Standard laboratory stocks.

      (Boyd and Harris, 1985)
      Comments
      Comments

      Mutation is recessive.

      (Boyd and Harris, 1987, Boyd and Harris, 1985)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      phr1
      Name Synonyms
      Secondary FlyBase IDs
        References (3)