FB2026_03 , released September 17, 2026
Allele: Dmel\Ppb1
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General Information
Symbol
Dmel\Ppb1
Species
D. melanogaster
Name
FlyBase ID
FBal0013942
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

Ppb[+]/Ppb1 is a suppressor of abnormal visual behavior phenotype of sev1

Ppb[+]/Ppb1 is a suppressor of abnormal phototaxis phenotype of sev1

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Dominant mutation that reverses the color-choice behavior of sev1 mutants - i.e. sev1; Ppb1/+ flies, like wild-type flies, prefer UV over green light, while sev1;+/+ flies prefer green over UV. When tested in a T-maze for preference between darkness and green light (550 nm), both wild type and sev1 flies show positive phototaxis, while sev1;Ppb1/+ and sev1;Ppb1/Ppb1 flies show negative phototaxis. Similarly, tests in a countercurrent apparatus for movement toward and movement away from white light indicate marked preference of wild-type flies for light and of sev1;Ppb1/+ flies for darkness. Both the positive phototactic response of sev1 and the negative phototactic response of sev1;Ppb1/+ flies increase with age, reaching a maximum at 4-6 days. The interaction between Ppb and sev is allele-specific, as is indicated in the sev allele entries. Photoreceptor cell R7, missing in all of the sev alleles, was not restored in any mutant combination of Ppb and sev.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Ppb1
Name Synonyms
Secondary FlyBase IDs
    References (1)