FB2026_03 , released September 17, 2026
Allele: Dmel\ref(2)Po2
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General Information
Symbol
Dmel\ref(2)Po2
Species
D. melanogaster
Name
FlyBase ID
FBal0014524
Feature type
allele
Associated gene
Dmel\ref(2)P
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Wayne et al., 1996, Dru et al., 1993)
Progenitor genotype
Cytology
Description

Sequence of ref(2)Po2 differs from that for ref(2)Po1 by four point mutations. Three are in coding regions for exon 2 or 3, where a serine in ref(2)Po1 is replaced by an arginine in ref(2)Po2, an aspartic acid by a glutamic acid and a threonine by a serine.

(Dru et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
X69829
CAA49483
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Permissive for sigma virus multiplication.

    (Dru et al., 1993)
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Permissive (susceptible) line to the sigma virus, determined by a CO2 sensitivity assay.

    (Wayne et al., 1996)
    External Crossreferences and Linkouts ( 3 )
    Crossreferences
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    ref(2)PO2
    (Carre-Mlouka et al., 2007)
    ref(2)Po2
    Name Synonyms
    Secondary FlyBase IDs
      References (3)