FlyBase Allele Report: Dmel\Polr2A[108]

General Information

Symbol

Dmel\Polr2A¹⁰⁸

Species

D. melanogaster

Name

FlyBase ID

FBal0014765

Feature type

allele

Associated gene

Dmel\Polr2A

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Mortin and Kaufman, 1982)

Mutagen

ethyl methanesulfonate

(Perrimon et al., 1984)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

cell lethal | germline clone

(Perrimon et al., 1984)

lethal | recessive

(Krasnoselskaya et al., 1998, Kim et al., 1994)

lethal - all die during embryonic stage

(Perrimon et al., 1984)

lethal - all die during embryonic stage | recessive

(Perrimon et al., 1989)

some die during embryonic stage

(Perrimon et al., 1984)

some die during embryonic stage | recessive

(Perrimon et al., 1989)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S1

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S2

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S5

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S6

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S8

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S7

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S11

(Kim et al., 1994)

Polr2A¹⁰⁸ has lethal phenotype, non-suppressible by Polr2B^S12

(Kim et al., 1994)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The recessive lethality of RpII215¹⁰⁸ is not rescued by one copy of RpII140^S1, RpII140^S2, RpII140^S5, RpII140^S6, RpII140^S8, RpII140^S7, RpII140^S11 or RpII140^S12.

(Kim et al., 1994)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Lefevre.

Comments

Maternal germline clonal analysis demonstrates cell lethality in homozygous clones.

(Perrimon et al., 1989)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

DF912

(Perrimon et al., 1989)

Polr2A¹⁰⁸

RpII215¹⁰⁸

RpIIⁿ²

(Mortin and Kaufman, 1982)

Ublⁿ²

l(1)DF912

(Perrimon et al., 1984)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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