FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rux2
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General Information
Symbol
Dmel\rux2
Species
D. melanogaster
Name
FlyBase ID
FBal0014882
Feature type
allele
Associated gene
Dmel\rux
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Adult eyes rough and reduced. Ommatidia and rhabdomeres are variable shape and size with an irregular arrangement. Clusters on eye disc are of variable size and shape.

        (Renfranz and Benzer, 1989)

        Homozygotes have rough eyes.

        (Lewis, 1945)

        male fertile female fertile

        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        rux2 is a suppressor of visible phenotype of upd1GMR.PB

        (Mukherjee et al., 2006)
        Phenotype Manifest In
        NOT Enhanced by
        Statement
        Reference

        rux2 has phenotype, non-enhanceable by E(S)1

        (Lewis, 1945)
        Suppressor of
        Statement
        Reference

        rux2 is a suppressor of eye phenotype of upd1GMR.PB

        (Mukherjee et al., 2006)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        E(S)1 has little or no effect on the rough eye phenotype in ecunspecified E(S)1 double heterozygotes.

        (Lewis, 1945)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (1)
        Stocks (2)
        Notes on Origin
        Discoverer

        Curry, 1st Dec. 1937.

        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        2
        (Mukherjee et al., 2006)
        rux2
        (Popodi et al., 2010-, Christensen et al., 2008.12.28)
        Name Synonyms
        Secondary FlyBase IDs
          References (7)