FB2026_02 , released June 18, 2026
Allele: Dmel\seg1
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General Information
Symbol
Dmel\seg1
Species
D. melanogaster
Name
FlyBase ID
FBal0015407
Feature type
allele
Associated gene
seg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eggs derived from seg1 females are shorter and broader than normal, although the density of blastoderm nuclei and egg volume is not affected. Segmentation is usually normal.

      (Tearle and Nusslein-Volhard, 1987)

      Eggs laid by homozygous females are 20% shorter and 10% broader than wild-type. The eggs are fertilised and development is usually normal. Gonads from seg1 female larvae transplanted into wild-type hosts produce short, fat eggs after eclosion.

      (Wieschaus et al., 1981)

      Eggs of homozygous females 20% shorter and 10% wider than normal; volume and density of blastoderm nuclei unchanged. Defect in somatic tissue inferred from normal phenotype of germ-line clones (Wieschaus).

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Germ line clonal analysis shows that seg function is required in the soma.

      (Wieschaus et al., 1981)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      seg
      (Wieschaus et al., 1981)
      seg1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)