FB2026_03 , released September 17, 2026
Allele: Dmel\snl1
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General Information
Symbol
Dmel\snl1
Species
D. melanogaster
Name
FlyBase ID
FBal0015913
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
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Allele class
Mutagen
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Expression Data
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Marker for
Reflects expression of
Reporter construct used in assay
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Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Maternal-effect recessive lethal or semi-lethal. snl1/snl1 females crossed to normal males produce fewer that 10% of the expected number of sons. Lethality can be rescued by a paternally derived snl+ allele as demonstrated by the survival of exceptional sons but not daughters (i.e., snl+/0 but not snl1/snl1/Y) of the above mating. Lethality occurs during embryonic or early larval stages. snl1/+ females crossed to snl1/Y males produce normal offspring in a 1:1 sex ratio. Crosses between snl1 males and females are nearly sterile, producing extreme sex ratios favoring females among surviving offspring. Data indicate that homozygosity for tra enhances and for dsx reduces the lethality of sons of snl1 mothers. Complements both r and fu, nearby genes that also act as maternal-effect lethals.

Homozygous females produce less than 10% male offspring regardless of male genotype. Females are phenotypically indistinguishable fro wild type. Lethal action occurs during the embryonic and early larval stages.

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Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
snl1
Name Synonyms
Secondary FlyBase IDs
    References (2)