FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\su(f)6
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General Information
Symbol
Dmel\su(f)6
Species
D. melanogaster
Name
FlyBase ID
FBal0016271
Feature type
allele
Associated gene
Dmel\su(f)
Associated Insertion(s)
Carried in Construct
Also Known As
su(f)X2, X-2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Perrimon et al., 1989, Schalet and Lefevre, 1973, Lifschytz and Falk, 1968)
Progenitor genotype
Cytology
Description

1110bp deletion, from nucleotide position 379-1488 (coordinates from FBrf0058525), starts from exon 1 and extends to the 5' half of exon 4.

(Simonelig et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:23,097,631..23,098,740 [+]
Comment:

1110 base deletion beginning upstream of the su(f) initiator Met and extending into exon 4.

(Simonelig et al., 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs during larval or pupal stages. Homozygous germline clones display cell lethality. Embryos derived from heterozygous mothers exhibit neither CNS or PNS defects.

      (Perrimon et al., 1989)

      su(f)4/su(f)6 females are fully viable and normal at 17-18oC, vary in viability and show a broad streak of dark pigment on the thorax at 24-25oC, but die some time before puparium formation at 29-30oC.

      (Schalet and Lefevre, 1973)

      su(f)4/su(f)6 females are fully viable and normal at 17-18oC. At 24-25oC, they vary in viability, show a broad streak of dark pigment on the thorax which is sometimes concentrated at the dorsal anterior region and have wings which sometimes stick up and out. At 29-30oC, they die just prior to puparium formation. su(f)6/su(f)1 shows a Minute-like phenotype at 24-25oC and results in lethality at 29-30oC.

      (Schalet, 1972)

      Homozygotes lethal at the larval stage; homozygous germ-line clones don't survive; no effect on development of peripheral or central nervous systems (Perrimon, Smouse, and Miklos, 1989). Lethal with su(f)3 at 25oC and with su(f)4 at 29oC.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially complements

      su(f)4

      (Schalet, 1972)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Lifschytz.

      Comments
      Comments

      su(f)6 complements su(f)4 only at 25oC. The allelic state of z has no effect on complementation behaviour.

      (Simonelig et al., 1996)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      X-2
      (Schalet and Lefevre, 1973, Lifschytz and Falk, 1969)
      X2
      (Lifschytz and Falk, 1968)
      l(1)X2
      su(f)6
      su(f)X-2
      (Schalet, 1972)
      su(f)X2
      (Simonelig et al., 1996, Perrimon et al., 1989)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)