FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tsg2
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General Information
Symbol
Dmel\tsg2
Species
D. melanogaster
Name
FlyBase ID
FBal0017192
Feature type
allele
Associated gene
Dmel\tsg
Associated Insertion(s)
Carried in Construct
Also Known As
tsgN9
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Mason et al., 1994)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mitotic domains 1, 5 and 6 expand and fuse across the dorsal midline in homozygous embryos. These mitotic domains are restored to the normal bilateral symmetry seen in wild-type embryos in homozygous embryos carrying tsgtwi.PM.

      (Mason et al., 1997)

      Suppression of tor13D embryos: increase in proportion of embryos that formed cuticle and decrease in proportion of embryos that formed empty sacs.

      (Strecker et al., 1991)

      embryonic lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      tsg2/tsg[+] is an enhancer of abnormal neuroanatomy phenotype of Ppt1UAS.cKa, Scer\GAL4GMR.PF

      (Saja et al., 2010)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      tsg2/tsg[+] is an enhancer of eye phenotype of Ppt1UAS.cKa, Scer\GAL4GMR.PF

      (Saja et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A tsg2/+ background enhances the visual system degeneration seen in Scer\GAL4GMR.PF, Ppt1Scer\UAS.cKa flies.

      (Saja et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (13)