FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tyr11
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General Information
Symbol
Dmel\tyr11
Species
D. melanogaster
Name
FlyBase ID
FBal0017327
Feature type
allele
Associated gene
tyr1
Associated Insertion(s)
Carried in Construct
Also Known As
tyr-1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description

Low phenol oxidase activity; activator preparations from as efficient as those from wild type.

(Pentz et al., 1990)

Dopamine levels 70% of those of wild-type.

(Burnell and Daly, 1982)

Mutant homozygotes have about 10% of the phenol oxidase activity of most wild-type strains. 50 h mutant pupae lack activity for the proenzyme PHOX and have detectable but reduced amounts of the diphenol oxidase components A1, A2 and A3 as compared to Samarkand wild-type pupae.

(Warner et al., 1974)

Phenol oxidase less heat stable than in wild-type (not confirmed by FBrf0045547).

(Lewis and Lewis, 1963)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults are normal size and have normal fertility and longevity. Body colour: body and bristle colour of adults is slightly yellower than normal.

      (Pentz et al., 1990)

      Body colour: underpigmented; less so than qs1. Hemolymph of adult fails to turn black on exposure to air; that of larva does.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      No discernible mutant phenotype in larvae.

      (Pentz et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tyr-1
      (Rizki et al., 1985, Batterham and MacKechnie, 1980)
      tyr11
      (Jordan et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)