FB2026_02 , released June 18, 2026
Allele: Dmel\U1
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General Information
Symbol
Dmel\U1
Species
D. melanogaster
Name
FlyBase ID
FBal0017332
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Progenitor genotype
Caused by aberration
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Heterozygotes exhibit curly upturned wings, crossed posterior scutellars and darker than normal body colour. Transheterozygotes with U2 exhibit the same phenotype.

Viable over U2 and Df(2L)C'. Wing phenotype is additive with that of Cy1. Though originally described as causing upwardly curled wings, crossed posterior scutellar bristles, darker than normal body color with dark waxy wings, and eyes mottled with light flecks, only upturned wings, crossed posterior scutellars, and darker than normal body color are currently observed in U1 and U2 heterozygotes and U1/U2 heteroalleles. Since U1 is associated with a pericentric inversion with one break in proximal 2L heterochromatin, perhaps U1 was originally recovered in combination with a lt-bearing homologue and the eye mottling resulted from variegation associated with removal of the lt locus from its normal heterochromatic to a distal euchromatic environment in In(2LR)U; U1/lt- flies exhibit variegated eyes in addition to upturned wings, crossed postscutellar bristles, and darker body color.

RK2A. Wings upturned like those of Cy1 but dark and waxy. Postscutellars bristles crossed as in cu1. Body colour: darker than normal. Eye colour: mottled with light flecks.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (1)
Stocks (2)
Notes on Origin
Discoverer

Ball, 27th Jan. 1932.

Comments
Comments

Phenotype is incompletely penetrant, being less reliable in males than in females. Chromosome is homozygous lethal, due to a second site lethal mutation. Dp(2;Y)G does not cover the lethality of In(2LR)U.

Chromosome carries a second site lethal mutation located at neither the 40F or 53A breakpoints of the inversion. Phenotype exhibits reduced penetrance, depending on genetic background, being less reliable in males than in females.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
U1
Name Synonyms
Secondary FlyBase IDs
    References (4)