FlyBase Allele Report: Dmel\w[sp3]

General Information

Symbol

Dmel\w^sp3

Species

D. melanogaster

Name

FlyBase ID

FBal0018304

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Davison et al., 1985, Zachar and Bingham, 1982)

Progenitor genotype

Cytology

Description

Deletion of sequences in the 5' regulatory region.

(Bhadra et al., 1997)

Deficiency in 5' regulatory region.

(Bhadra and Birchler, 1996)

Deficiency in 5' cis-regulatory region.

(Chapman and Bingham, 1985)

17kb deletion that starts between nucleotide position -925 and -870.

(Davison et al., 1985)

Deletion from coordinates +5 to +5.9 through to coordinates +21.9 to +22.1, using coordinate system of FBrf0038648 where coordinate 0 is the copia insert of w^a.

(Zachar and Bingham, 1982)

deletion map site (kb): +5 to +22; Origin = insertion of w^a copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Bhadra et al., 1997)

abnormal eye color | recessive

(Frolov et al., 1998)

visible | recessive

Phenotype Manifest In

pigment cell

(Benevolenskaya et al., 1998, Frolov et al., 1998)

testis pigment cell

Detailed Description

Statement

Reference

Eye colour: yellowish to brown; fine-grained mottling; male darker than female. Testis colour: colourless.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

w^sp3 has abnormal eye color | recessive phenotype, suppressible by Rga[+]/Rga⁰³⁸³⁴

(Frolov et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^sp3 has pigment cell phenotype, enhanceable by RpLP0⁰¹⁵⁴⁴

(Frolov and Birchler, 1998)

w^sp3 has phenotype, enhanceable by Mow^gamma

(Bhadra and Birchler, 1996)

NOT Enhanced by

Statement

Reference

w^sp3 has phenotype, non-enhanceable by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^sp3 has phenotype, non-enhanceable by Low¹

(Bhadra et al., 1997)

w^sp3 has phenotype, non-enhanceable by Ufo¹

(Bhadra et al., 1997)

Suppressed by

Statement

Reference

w^sp3 has pigment cell phenotype, suppressible by Rga[+]/Rga⁰³⁸³⁴

(Frolov et al., 1998)

w^sp3 has phenotype, suppressible by east¹

(Chapman and Bingham, 1985)

NOT suppressed by

Statement

Reference

w^sp3 has phenotype, non-suppressible by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^sp3 has phenotype, non-suppressible by Low¹

(Bhadra et al., 1997)

w^sp3 has phenotype, non-suppressible by Ufo¹

(Bhadra et al., 1997)

Other

Statement

Reference

sgl⁰⁵⁰⁰⁷, w^sp3 has pigment cell phenotype

(Benevolenskaya et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

101255

y¹ w^sp3

Notes on Origin

Discoverer

Green, 29th Jan. 1959.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

w^sp3

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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