FB2026_03 , released September 17, 2026
Allele: Dmel\G6pdAF2
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General Information
Symbol
Dmel\G6pdAF2
Species
D. melanogaster
Name
FlyBase ID
FBal0018867
Feature type
allele
Associated gene
Dmel\G6pd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Eanes et al., 1996)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C942T. Amino acid replacement: R119C. Residue 382 is Leu.

(Eanes et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
sequence_variant
X:19,670,881..19,670,881 [+]
Nucleotide change:

C19564914T

Reported nucleotide change:

C942T

Amino acid change:

R119C | G6pd-PA; R97C | G6pd-PB; R97C | G6pd-PC

Reported amino acid change:

R119C

Comment:

Mutation presumed to be responsible for electrophoretic variant.

(Eanes et al., 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Z19019
Z19020
Z19048
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      electrophoretic variant: faster than ZwA suppression of Pgd-lethality: strong

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Eanes.

      Isolated from: Mt. Sinai, NY population. Isolated from: St. James, NY population. Isolated from: Lincoln, MA population.

      (Eanes et al., 1996)
      External Crossreferences and Linkouts ( 3 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      G6pdAF2
      ZwAF2
      ZwAF3
      ZwAF4
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0018868
      • FBal0018869
      References (2)