FB2026_03 , released September 17, 2026
Allele: Dmel\G6pdAS2
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General Information
Symbol
Dmel\G6pdAS2
Species
D. melanogaster
Name
FlyBase ID
FBal0018871
Feature type
allele
Associated gene
Dmel\G6pd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
Progenitor genotype
Cytology
Description

Amino acid replacement: D384N.

(Eanes et al., 1996)

Residue 382 is Pro.

(Eanes et al., 1996)

Nucleotide substitution: G1822A.

(Eanes et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
sequence_variant
X:19,671,761..19,671,761 [+]
Nucleotide change:

G19565794A

Reported nucleotide change:

G1822C

Amino acid change:

D384N | G6pd-PA; D362N | G6pd-PB; D362N | G6pd-PC

Reported amino acid change:

D384N

Comment:

The reported nucleotide change is in error. It should be a G to A change to achieve the reported Ser to Asn amino acid change. The mutation is presumed to be responsible for the electrophoretic variant.

(Eanes et al., 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Z19031
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      electrophoretic variant: slower than ZwA suppression of Pgd-lethality: moderate

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Eanes.

      Isolated from: Ft. Pierce, FL population.

      (Eanes et al., 1996)
      Comments
      Comments

      FlyBase Curator Comment: The nucleotide change is reported in the paper as G1822C, but it has to be G1822A in order to get the D to N amino acid change.

      (Eanes et al., 1996)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      G6pdAS2
      ZwAS2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)