FB2026_02 , released June 18, 2026
Allele: Dmel\eaghd15
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General Information
Symbol
Dmel\eaghd15
Species
D. melanogaster
Name
FlyBase ID
FBal0028170
Feature type
allele
Associated gene
Dmel\eag
Associated Insertion(s)
P{}eaghd15
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
(Drysdale et al., 1991)
Progenitor genotype
Associated Insertion(s)
P{}eaghd15
Cytology
Description

Insertion of a P element of 0.6kb length at coordinate +25.

(Drysdale et al., 1991)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous adults show a reduced response to propionic acid, ethyl butyrate, 2-butanone and ethyl acetate in an electroantennogram assay compared to control flies. The response to butanol, 1-octanol, benzaldehyde, butyl acetate and 2-heptanone in this assay is not significantly different from the response of control flies to these odorants. Mutant flies have fewer antennal neurons that are sensitive to ethyl butyrate than control flies.

      (Dubin et al., 1998)

      Homozygotes show increased sensitivity to trichloroethylene and halothane, but not to chloroform in an inebriometer assay (an assay of geotactic and postural behaviour) compared to wild-type flies.

      (Leibovitch et al., 1995)

      Ether induced leg shaking and electrophysiological defect characteristic of eag mutations.

      (Drysdale et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Reverts to wild type under dysgenic conditions, with loss of P element from eag region.

      (Drysdale et al., 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      eaghd15
      Name Synonyms
      Secondary FlyBase IDs
        References (3)