FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ptc7
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General Information
Symbol
Dmel\ptc7
Species
D. melanogaster
Name
FlyBase ID
FBal0028497
Feature type
allele
Associated gene
Dmel\ptc
Associated Insertion(s)
Carried in Construct
Also Known As
ptc9b28, ptc9B
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hidalgo and Ingham, 1990, Phillips et al., 1990, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ptchdl animals transheterozygous for ptc7 are viable with lowly penetrant headcase defects and show lowly penetrant locomotor defects in adulthood.

      (Gazi et al., 2009)

      ptchdl in combination with ptc7 does not lead to any head capsule defects.

      (Shyamala and Bhat, 2002)

      Clones induced in the second instar larvae eye disc are relatively small and have only minor effects on disc growth and morphology.

      (Heberlein et al., 1998)

      Stage 12 wgl-12 ptc7 double mutants embryos exhibit ectopic dorsal median cells that have aberrant segmental organisation. By stage 15 dorsal median cells have expanded along the entire anterior/posterior length of the midline.

      (Zhou et al., 1997)

      homozygous lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      References (11)