FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\S126
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General Information
Symbol
Dmel\S126
Species
D. melanogaster
Name
FlyBase ID
FBal0030174
Feature type
allele
Associated gene
Dmel\S
Associated Insertion(s)
P{}S126
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Heberlein et al., 1993, Heberlein and Rubin, 1991)
Progenitor genotype
Associated Insertion(s)
P{}S126
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous mutant clones in the developing eye induces apoptotic cells in the eye, but only about 10 ommatidial columns posterior to the morphogenetic furrow.

      (Hsiung et al., 2001)

      Dorsal medial cell numbers vary between 2 and 6 per embryo.

      (Luer et al., 1997)

      Heterozygous flies have essentially wild-type eyes. Homozygous clones in the eye are always associated with a scar, surrounded by normal ommatidia of mixed genotype.

      (Heberlein and Rubin, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Enhances the ro phenotype: eyes from rox63/rox63, S126/+ double mutant flies are severely reduced in size and disorganised, and individual ommatidia contain only 3-4 photoreceptors.

      (Heberlein and Rubin, 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      S126
      Name Synonyms
      Secondary FlyBase IDs
        References (4)