FB2026_02 , released June 18, 2026
Allele: Dmel\Sxlfc
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General Information
Symbol
Dmel\Sxlfc
Species
D. melanogaster
Name
FlyBase ID
FBal0030317
Feature type
allele
Associated gene
Dmel\Sxl
Associated Insertion(s)
?{}Sxlfc
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Granadino et al., 1991)
Progenitor genotype
Associated Insertion(s)
?{}Sxlfc
Cytology
Description

Insertion of approximately 5kb DNA between -10 and -11 (coordinates as in FBrf0042036), within the fourth intron.

(Granadino et al., 1991)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Sxlf7,M1/Sxlfc females do not develop ovaries, though germ cells of this genotype transplanted into wild-type hosts produce functional oocytes, suggesting that it is in the somatic cells of this genotype that the ovaries are affected.

      (Granadino et al., 1993)

      Fully complements SxlfLS. Homozygous females show a high degree of lethality; 70% die as embryos, 28% die as larvae. Those that survive are normal females. Homozygous clones also develop female structures. Homozygous germ cell clones give rise to functional eggs. Sxlf7,M1/Sxlfc flies lack gonads and occasionally have a male spot on the fifth and sixth tergites. Viability is greatly reduced in heterozygous combination with Df(1)N71 or Df(1)svr.

      (Granadino et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Analysis of the amount of transcription or enzyme activity of a number of autosomal and X-linked genes in homozygous larvae suggests that this mutation does not affect late dosage compensation.

      (Granadino et al., 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Sxlfc
      Name Synonyms
      Secondary FlyBase IDs
        References (2)