FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\eyaE3
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General Information
Symbol
Dmel\eyaE3
Species
D. melanogaster
Name
FlyBase ID
FBal0030768
Feature type
allele
Associated gene
Dmel\eya
Associated Insertion(s)
Carried in Construct
Also Known As
eyaE3ts
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Bonini et al., 1998, Bonini et al., 1993)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      eyaE3/eya1 flies and eyaE3/eya3 flies have eyes that are between 3/4 and less than normal size.

      (Bonini et al., 1998)

      50% to less than 100% of eyaE3/Df(2L)eya10 embryos hatch. 50% to less than 100% of homozygous animals survive to adulthood. Adults have eyes which range from 1/2 to less than normal size. eyaE3/eya4 flies have eyes which range from 1/2 to less than normal size. Viable in transheterozygous combination with eya1, eya2, eya3 or eya4, producing flies with eyes that range from 1/2 to less than normal size. Transheterozygotes in combination with eyaE9, eyaE2, eyaE8, eyaE5, eyaE10, eyaD4, eyaZ283, eyaD2, eyaD3, eyaD6 or eyaD7 do not survive to adulthood. Transheterozygotes in combination with eyaE6, eyaE11, eyaE4, eyaE12, eyaE7, eyaE1, eyaD5, eyaD1 or eyacli-IID show reduced survival to adulthood, and produce flies with smaller eyes than normal.

      (Leiserson et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially complements

      eya1

      (Bonini et al., 1993)
      Comments

      Fails to complement eye phenotype of eya1.

      (Bonini et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      clieya-E3
      eyaE3
      eyaE3ts
      (Bui et al., 2000, Bonini et al., 1998, Leiserson et al., 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)