FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\crnyok-EH160
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General Information
Symbol
Dmel\crnyok-EH160
Species
D. melanogaster
Name
FlyBase ID
FBal0030960
Feature type
allele
Associated gene
Dmel\crn
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Eberl and Hilliker, 1988)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most of the cells of the Malpighian tubules of homozygous embryos fail to undergo rearrangement to form tubes with a two cell circumference. Only cells at the distal end of the tubule rearrange.

      (Jack and Myette, 1999)

      Hemizygotes display defects in CNS and PNS development. CNS has significantly fewer axons to make up the longitudinal connectives and the intersegmental and segmental nerves in embryos. The PNS has few or no chordotonal organs. Midgut constrictions do not appear, late embryos have a solid yolk plug.

      (Zhang et al., 1991)

      Yolk plug, no Malpighian tubules.

      (Eberl and Hilliker, 1988)

      embryonic lethal undispersed yolk plug and no visible Malpighian tubules. Cuticle phenotype normal.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      crny0kEH160
      (Jack and Myette, 1999)
      crnyok-EH160
      l(1)EH160
      yokEH160
      (Eberl and Hilliker, 1988)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)