FlyBase Allele Report: Dmel\hry[L43a]

General Information

Symbol

Dmel\hry^L43a

Species

D. melanogaster

Name

FlyBase ID

FBal0031443

Feature type

allele

Associated gene

Dmel\hry

Associated Insertion(s)

P{A92}hry^L43a

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Davis et al., 1993, Orenic et al., 1993, Fasano et al., 1988)

Progenitor genotype

Associated Insertion(s)

P{A92}hry^L43a

Cytology

Description

P{A92} insertion into the h stripe element region of the promoter.

(Davis et al., 1993)

P{A92} inserted within 12bp of the proximal initiation site, in the 5' leader of the longer h transcript.

(Lardelli and Ish-Horowicz, 1993)

Insertion of P{A92} into 5' end of protein coding sequence.

(Orenic et al., 1993)

An "enhancer trap" transposon containing Ecol\lacZ is inserted near the h transcription start site.

(Riddihough and Ish-Horowicz, 1991)

P{A92} insertion in the 5' region of the h gene in the same orientation as h transcription.

(Fasano et al., 1988)

Allele components

Component

Use(s)

Inserted element

P{A92}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:8,675,940..8,675,951 [+]

(Davis et al., 1993, Lardelli and Ish-Horowicz, 1993, Orenic et al., 1993, Riddihough and Ish-Horowicz, 1991, Fasano et al., 1988)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Orenic et al., 1993, Fasano et al., 1988)

pair rule phenotype

(Fasano et al., 1988)

pair rule phenotype | embryonic stage | recessive

(Fasano et al., 1988)

some die during embryonic stage | recessive

(Orenic et al., 1993, Fasano et al., 1988)

Phenotype Manifest In

embryo

(Fasano et al., 1988)

macrochaeta

(Fasano et al., 1988)

Detailed Description

Statement

Reference

Transheterozygotes with h²⁷ and hⁱ²² are lethal, strong pair-rule phenotype and transheterozygotes with h² have an extra chaetae phenotype.

(Fasano et al., 1988)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36545

P{A92}hry^L43a kar¹ ry^*/TM3, Sb¹

Notes on Origin

Discoverer

Comments

h expression in the embryo reduced in the anterodorsal domain but not the stripes.

(Lardelli and Ish-Horowicz, 1993)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

P(Lac,ry+)L43a

(Lardelli and Ish-Horowicz, 1993)

h^L43a

hry^L43a

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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