FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hryhs.P1
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General Information
Symbol
Dmel\hryhs.P1
Species
D. melanogaster
Name
FlyBase ID
FBal0031448
Feature type
allele
Associated gene
Dmel\hry
Associated Insertion(s)
Carried in Construct
P{HSH1}
P{HSH3}
P{HSH}
Key Links
Transgenic product class
cDNA
(Ish-Horowicz and Pinchin, 1987)
wild_type
(Ish-Horowicz and Pinchin, 1987)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ish-Horowicz and Pinchin, 1987)
wild_type
(Ish-Horowicz and Pinchin, 1987)
Mutagen
in vitro construct
(Jimenez et al., 1997, Skeath and Carroll, 1991, Rushlow et al., 1989, Ish-Horowicz and Pinchin, 1987)
Progenitor genotype
Carried in construct
P{HSH1}
P{HSH3}
P{HSH}
Cytology
Description

h cDNA expression is driven by an Hsp70 promoter region including 250bp upstream of the start of transcription. The 3' end of the transcription unit derives from h.

(Ish-Horowicz and Pinchin, 1987)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
hry
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of h does not affect cell number in the stalks between egg chambers.

      (Forbes et al., 1996)

      Heat induced h expression causes two classes of cuticular patterns defects. One is 'pair-rule' embryos display pair-wise fusions of adjacent metameres. The second show more extreme deletions, in particular fusion of A2-A7 denticle bands to produce a 'lawn' embryo. The temperature sensitive period for each phenotype has been determined. Heat shock 5-20 minutes before gastrulation produces the pair-rule phenotype alone, 20-35 minutes before gastrulation produces the pair-rule and lawn phenotype and 35-50 minutes before gastrulation produces the lawn phenotype alone.

      (Ish-Horowicz and Pinchin, 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      hryhs.P1 is a suppressor of macrochaeta | ectopic phenotype of acHw-1

      (Rushlow et al., 1989)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      hryhs.P1 rescues hry1

      (Rushlow et al., 1989)

      hryhs.P1 rescues hry2

      (Rushlow et al., 1989)
      Comments

      Early pupae heat shocked for 1 hour at 36oC exhibit complete suppression of extra bristles on the L2 wing vein of h1 and h2 wings. The temperature sensitive period is day one of pupal development.

      (Rushlow et al., 1989)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hhs.P1
      hryhs.P1
      Name Synonyms
      Secondary FlyBase IDs
        References (7)