FB2026_02 , released June 18, 2026
Allele: Dmel\mEFG1GA1
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General Information
Symbol
Dmel\mEFG1GA1
Species
D. melanogaster
Name
FlyBase ID
FBal0031688
Feature type
allele
Associated gene
Dmel\mEFG1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tiong and Nash, 1990)
Progenitor genotype
Cytology
Description

Amino acid replacement: V214E.

(Trivigno and Haerry, 2011)

Amino acid replacement: E216K.

(Trivigno and Haerry, 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:7,222,242..7,222,242 [-]
Nucleotide change:

G7222242A

Amino acid change:

E216K | mEFG1-PA

Reported amino acid change:

E216K

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Trivigno and Haerry, 2011)
point_mutation
2L:7,222,247..7,222,247 [-]
Nucleotide change:

T7222247A

Amino acid change:

V214E | mEFG1-PA

Reported amino acid change:

V214E

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Trivigno and Haerry, 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      dpphr4, mEFG1GA1/l(2)27Ea[+] has lethal | embryonic stage phenotype

      (Trivigno and Haerry, 2011)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      icoGA1/+, dpphr4/+ animals die as embryos.

      (Trivigno and Haerry, 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of icoScer\UAS.cTa under the control of Scer\GAL4arm.PS and Scer\GAL4da.G32 rescues the lethality of icoGA1/icoDel-EY2.

      (Trivigno and Haerry, 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      GA1
      (Trivigno and Haerry, 2011)
      icoGA1
      (Trivigno and Haerry, 2011)
      l(2)27Ea1
      mEFG1GA1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)