FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mdyRF48
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General Information
Symbol
Dmel\mdyRF48
Species
D. melanogaster
Name
FlyBase ID
FBal0032114
Feature type
allele
Associated gene
Dmel\mdy
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description

Amino acid replacement: V477D.

(Buszczak et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:16,826,388..16,826,388 [+]
Nucleotide change:

T16826388A

Amino acid change:

V477D | mdy-PA; V477D | mdy-PB; V477D | mdy-PC; V477D | mdy-PE

Reported amino acid change:

V477D

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Buszczak et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      nurse cell & nuclear membrane

      (Buszczak et al., 2002)
      Detailed Description
      Statement
      Reference

      Nurse cell nuclear membrane becomes permeable prematurely.

      (Buszczak et al., 2002)

      Egg chambers begin to arrest at stage 8 or 9 and begin to degenerate.

      (Schupbach and Wieschaus, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mdyRF48
      mdyrf48
      (Buszczak et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)