FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\cas39
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General Information
Symbol
Dmel\cas39
Species
D. melanogaster
Name
FlyBase ID
FBal0032146
Feature type
allele
Associated gene
Dmel\cas
Associated Insertion(s)
P{?lacW}cas39
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Cui and Doe, 1992)
Mutagen
Delta2-3 transposase
(Cui and Doe, 1992)
Progenitor genotype
cas2092
(Cui and Doe, 1992)
Associated Insertion(s)
P{?lacW}cas39
Cytology
Description

Small deletion. A functional Ecol\lacZ gene (derived from the P{lacW} progenitor insertion) is still present.

(Grosskortenhaus et al., 2006)

Lacks genomic DNA flanking P element insertion of cas2092.

(Cui and Doe, 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos have ectopic U4 neurons in both thoracic and abdominal hemisegments.

      (Grosskortenhaus et al., 2006)

      Posterior commissure has only half the diameter of wild type embryos: one fasciclin III- positive fascicle is missing.

      (Cui and Doe, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Embryos expressing pdm2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4pros.PMG in a cas39/cas39 background have ectopic U4 neurons.

      (Grosskortenhaus et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      en expression in the CNS is abnormal.

      (Cui and Doe, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cas39
      (Fontana and Crews, 2012, Grosskortenhaus et al., 2006)
      ming39
      (Cui and Doe, 1992)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)