FB2026_02 , released June 18, 2026
Allele: Dmel\ninaAG98D
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General Information
Symbol
Dmel\ninaAG98D
Species
D. melanogaster
Name
FlyBase ID
FBal0032250
Feature type
allele
Associated gene
Dmel\ninaA
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ondek et al., 1992)
Progenitor genotype
Cytology
Description

Amino acid replacement: G98D.

(Ondek et al., 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:877,654..877,654 [+]
Nucleotide change:

G877654A

Amino acid change:

G98D | ninaA-PA

Reported amino acid change:

G98D

Comment:

Site of nucleic acid substitution inferred by FlyBase based on reported amino acid change

(Ondek et al., 1992)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Deep pseudopupil score of 5.

      (Ondek et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      ninaAG98D/ninaA[+] is a suppressor of increased cell death phenotype of p53UAS.cJa

      (Mendes et al., 2009)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ninaAG98D/ninaA[+] is a suppressor of outer photoreceptor cell phenotype of p53UAS.cJa

      (Mendes et al., 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Loss of one genomic copy of ninaA, in a ninaAG98D/+ background does not protect the outer photoreceptor cells from Scer\GAL4ninaE.PT;p53Scer\UAS.cJa-induced apoptosis.

      (Mendes et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      This particular substitution was isolated independently twice.

      (Ondek et al., 1992)

      Weak ninaE allele. Forms a stable complex with P{Rh1-His}.

      (Baker et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ninaAG98D
      (Mendes et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)