FlyBase Allele Report: Dmel\pros[m3]

General Information

Symbol

Dmel\pros^m3

Species

D. melanogaster

Name

FlyBase ID

FBal0032483

Feature type

allele

Associated gene

Dmel\pros

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Doe et al., 1991)

Mutagen

ethyl methanesulfonate

(Doe et al., 1991)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Doe et al., 1991)

lethal - all die during embryonic stage

(Doe et al., 1991)

some die during embryonic stage

(Doe et al., 1991)

Phenotype Manifest In

central nervous system

(Doe et al., 1991)

larval DA1 motor neuron

(Doe et al., 1991)

larval ventral nerve cord

(Doe et al., 1991)

pCC neuron

(Doe et al., 1991)

ventral midline of embryo

(Doe et al., 1991)

Detailed Description

Statement

Reference

Severe CNS defects. The aCC and pCC neurons have abnormal axon morphology. Cells involved in the circumferential or mediolateral condensation of the CNS may be defective: nerve cord condensation along the mediolateral axis is retarded and there are often gaps along the midline.

(Doe et al., 1991)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

pros^m3

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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