FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bcdΔ21.2BLE1.LZ
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General Information
Symbol
Dmel\bcdΔ21.2BLE1.LZ
Species
D. melanogaster
Name
FlyBase ID
FBal0034218
Feature type
allele
Associated gene
Dmel\bcd
Associated Insertion(s)
Carried in Construct
P{2xBLE1+}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Macdonald et al., 1995, MacDonald et al., 1993)
Progenitor genotype
bcdΔ21.LZ
(Macdonald et al., 1995)
Carried in construct
P{2xBLE1+}
Cytology
Description

Two tandem copies of the BLE1 element are fused to bcd sequences.

(Macdonald et al., 1995)

As for bcdΔ21.LZ i.e. a deletion of bases 4056-4726 (coordinates of FBrf0047926) in bcd 3' UTR, with addition of a 1.3kb Ecol\lacZ gene fragment to aid detection in in situ hybridizations, and with addition of two copies of that sequence deleted in bcdΔ14, the BLE.

(MacDonald et al., 1993)
Allele components
Component
Use(s)
Regulatory region(s)
bcd
Encoded product / tool
bcd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      oogenesis stage S5 -- S6
      oocyte | anterior
      (MacDonald et al., 1993)
      Additional Information
      Statement
      Reference

      During early stages ofoogenesis the bcdΔ21.2BLE1.T:EcollacZ transcript is localized similarlyto wild type bcd, however, as oocyte development proceeds the transcriptdiffuses throughout the oocyte.

      (MacDonald et al., 1993)
       
      Marker for
      Reflects expression of
      bcd
      (MacDonald et al., 1993)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Transcripts are localized in the oocyte, but only in the early steps of the bcd localization pathway.

      (MacDonald et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      bcdΔ21.2BLE1.LZ
      bcdΔ21.2BLE1.T:Ecol\lacZ
      bcdΔ21.2BLE1.T:lacZ
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0034214
      References (2)