FlyBase Allele Report: Dmel\bi[rb5]

General Information

Symbol

Dmel\bi^rb5

Species

D. melanogaster

Name

FlyBase ID

FBal0034306

Feature type

allele

Associated gene

Dmel\bi

Associated Insertion(s)

Carried in Construct

Also Known As

Df(1)rb5

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

Df(1)rb5

Cytology

Description

Distal breakpoint breaks the optic lobe regulatory region of bi.

(Brunner et al., 1992)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die (with bi¹²)

(Sen et al., 2010)

partially lethal - majority die (with bi¹³)

(Sen et al., 2010)

partially lethal - majority die (with bi¹⁵)

(Sen et al., 2010)

Phenotype Manifest In

horizontal system neuron

(Brunner et al., 1992)

optic chiasma

(Brunner et al., 1992)

wing (with bi¹²)

(Sen et al., 2010)

wing (with bi¹³)

(Sen et al., 2010)

wing (with bi¹⁵)

(Sen et al., 2010)

wing vein (with bi¹²)

(Sen et al., 2010)

wing vein (with bi¹³)

(Sen et al., 2010)

wing vein (with bi¹⁵)

(Sen et al., 2010)

Detailed Description

Statement

Reference

bi^rb5/bi¹² transheterozygotes lack HS/VS cells and exhibit increased lethality.

bi^rb5/bi¹³ transheterozygotes lack HS/VS cells and exhibit increased lethality.

bi^rb5/bi¹⁵ transheterozygotes lack HS/VS cells and exhibit increased lethality.

(Sen et al., 2010)

Heterozygotes with bi^omb-1 lack HS- and VS-neurons and display inner chiasm defects, small alterations to the fibre path.

(Brunner et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Df(1)rb5

(Sen et al., 2010, Hofmeyer et al., 2008)

bi^rb5

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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