Expression of a truncated vvl cDNA containing 111bp of 5' untranslated sequences and 580bp of 3' untranslated sequence is influenced by the Hsp70 promoter and α-tubulin polyadenylation sequences.
Heat induced expression disrupts commissure formation resulting in fusion of the longitudinal connectives at the midline.
Specific CNS defect displayed by lack of or defective commissural formation.