FB2026_02 , released June 18, 2026
Allele: Dmel\inIH52
Open Close
General Information
Symbol
Dmel\inIH52
Species
D. melanogaster
Name
FlyBase ID
FBal0039445
Feature type
allele
Associated gene
Dmel\in
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Park et al., 1996, Adler et al., 1994)
Mutagen
ethyl methanesulfonate
(Park et al., 1996, Adler et al., 1994)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C2407T.

(Park et al., 1996)

The premature stop codon is predicted to result in a truncated protein lacking the carboxy-terminal 107 amino acids.

(Park et al., 1996)

Amino acid replacement: Q763term.

(Park et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:20,369,602..20,369,602 [+]
Nucleotide change:

C20369602T

Reported nucleotide change:

C2407T

Amino acid change:

Q763term | in-PA

Reported amino acid change:

Q763term

(Park et al., 1996, Adler et al., 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Unmarked clones in all regions of the wing display an in phenotype, cells form more than one hair and hairs with an abnormal polarity. Marked clones in the wing indicate in acts autonomously, cells bordering clones are wild type.

      (Park et al., 1996)

      Viable as a homozygote or a hemizygote. Strong thoracic bristle and wing hair phenotype. Percentage of dorsal wing surface cells that display abnormal cell polarity and the percentage of wing cells forming more than one hair is more severe at 18oC than 29oC.

      (Adler et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Strong in allele.

      (Adler et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      inIH52
      Name Synonyms
      Secondary FlyBase IDs
        References (3)