FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZTm2.1Ba.hs
Open Close
General Information
Symbol
Ecol\lacZTm2.1Ba.hs
Species
E. coli
Name
FlyBase ID
FBal0042028
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Tm2(1Ba)lacZ}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lin et al., 1996, Gremke et al., 1993)
Progenitor genotype
Ecol\lacZhs.PS
(Gremke et al., 1993)
Carried in construct
P{Tm2(1Ba)lacZ}
Cytology
Description

Muscle activator region from the proximal muscle enhancer within the first intron of Tm2 drives expression of an Hsp70 promoter fused to lacZ.

(Lin et al., 1996)

Tm2 intron sequences from +413bp to +504bp governing expression of lacZ from an Hsp70 promoter.

(Gremke et al., 1993)
Allele components
Component
Use(s)
Regulatory region(s)
Tm2_intronI1B(a)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      larval muscle system
      (Gremke et al., 1993)
      adult stage
      adult muscle system | subset
      (Gremke et al., 1993)
      Additional Information
      Statement
      Reference

      In larva, expressed in all somatic and visceral muscles; level of expression lower relative to constructs carrying larger intron fragments. In adults, expressed in all somatic and visceral muscles of the head and abdomen; in adult thorax, expressed in somatic tubular muscles and in direct flight muscles, but not in the IMF (indirect flight muscles) or the TDT (tergal derepressor of the trochanters). In adults, also, the level of expression is lower relative to constructs carrying larger intron fragments.

      (Gremke et al., 1993)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZTm2.1Ba.hs
      lacZTm2.1Ba.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (5)