FB2026_03 , released September 17, 2026
Allele: Ecol\lacZzen:eve.VR:MSE
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General Information
Symbol
Ecol\lacZzen:eve.VR:MSE
Species
E. coli
Name
FlyBase ID
FBal0042302
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{lacZzen/eve.600bpVRE}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cai et al., 1996, Cai and Levine, 1995, Jiang et al., 1993, Jiang et al., 1992)
Progenitor genotype
Ecol\lacZeve.MSE
(Cai and Levine, 1995, Jiang et al., 1993, Jiang et al., 1992)
Carried in construct
P{lacZzen/eve.600bpVRE}
Cytology
Description

A 600bp XbaI-HindIII fragment carrying the complete zen ventral repression element (VRE) (sequence from -1.6 to -1.0kb relative to the zen transcription start site) is fused upstream of the eve MSE. The VRE is in the same orientation relative to the promoter as in the native zen promoter.

(Jiang et al., 1992)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic cycle 14A
      organism | dorsal
      (Jiang et al., 1992)
      embryonic cycle 14B
      organism | dorsal | striped
      (Jiang et al., 1992)
      Additional Information
      Statement
      Reference

      In stage 5 embryo, the ventral portion of the eve second stripe pattern is repressed; in addition, there is dorsal expression outside the eve second stripe. This results, during embryonic cycle 14A, in dorsal expression from the region of eve stripe 2 and more posterior; and during embryonic cycle 14B, in high levels of expression in the dorsal half of the eve stripe 2 region, with lower levels in more posterior dorsal regions.

      (Jiang et al., 1992)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Used in deletion analysis of repression/activation regions in zen VRE.

      (Jiang et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZzen:eve.VR/MSE
      Ecol\lacZzen:eve.VR:MSE
      lacZzen:eve.VR/MSE
      Name Synonyms
      Secondary FlyBase IDs
        References (6)