FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bbt13.2
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General Information
Symbol
Dmel\bbt13.2
Species
D. melanogaster
Name
FlyBase ID
FBal0042876
Feature type
allele
Associated gene
bb
Associated Insertion(s)
Carried in Construct
P{5'rib7.K+}
P{rib7}
Also Known As
rib7
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Perrin et al., 1998, Karpen et al., 1988)
Progenitor genotype
Carried in construct
P{5'rib7.K+}
P{rib7}
Cytology
Description

Encodes a single rDNA cistron.

(Rasooly and Robbins, 1991)

Construct: Included in a genomic 13.2kb NruI-BalI fragment containing nontranscribed spacer, external transcribed spacer, 18SrRNA, internal transcribed spacer, 28SrRNA and nontranscribed spacer DNA.

(Karpen et al., 1988)
Allele components
Component
Use(s)
Encoded product / tool
bb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      An X-linked copy of P{rib7} has no significant effect on the percentage of sex chromosome nondisjunction in T(1;4)mscd1 or T(1;4)mscd2 males.

      (Briscoe and Tomkiel, 2000)

      Improves disjunction percentages in Df(1)X-1/Dp(1;Y)BSYy+ males to 60-64% (single inserts) and 77% (double inserts). Male fertility and recovery of reciprocal products are also improved. Restores fertility to following aberrations in combination with Df(1)X-1 : T(Y;2)P59, T(Y;2)H143, T(Y;2)B80, T(Y;3)B240, T(Y;3)H173, T(Y;3)H163, T(Y;3)R133 and T(Y;2)H158. Increases fertility of Df(1)X-1; T(Y;2)B80 from 0 to 71.4 or 74.2% (depending on insert).

      (McKee et al., 1998)

      Increases the frequency of nondisjunction X-Y seen in Df(1)X-1/Dp(1;Y)BSYy+ males.

      (Ren et al., 1997)

      P{rib7} stimulates X-Y pairing and disjunction when inserted onto Df(1)X-1, but not when inserted on an autosome.

      (McKee and Karpen, 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      bbt13.2 rescues T(1;4)mscd1

      (Briscoe and Tomkiel, 2000)

      bbt13.2 rescues T(1;4)mscd2

      (Briscoe and Tomkiel, 2000)
      Partially rescues

      bbt13.2 partially rescues bb1

      (Karpen et al., 1988)
      Comments

      Autosomal copies of P{rib7} rescue the bb mutant phenotype of T(1;4)mscd1/0 or T(1;4)mscd2/0 males.

      (Briscoe and Tomkiel, 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      bbt13.2
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0034208
      References (12)