FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\en::ftzEFE.hs
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General Information
Symbol
Dmel\en::ftzEFE.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0043031
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Expression of the en-ftz fusion gene is driven by an Hsp70 promoter.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

After a 15 minute heat shock more than 70% embryos fail to hatch. More than 70% embryos exhibit preferential deletion of ftz-dependent bands of the ventral denticle belts. Co-expression of en::ftzEFE.F175E.hs reduces the number of embryos with pattern defects.

Expression induced between 2.5 and 3 hours of development causes pattern deletions predominantly in the ftz-dependent parasegments. Less severe phenotype is fusion of pairs of denticle belts often at the edges and loss of naked cuticle anterior to the ftz-dependent bands, or partial loss of bands without loss of naked cuticle.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Carried in plasmid "phs-EFE" and expressed in S2 cells.

Carried in plasmid "pEFE", expressed in S2 cells and competition for ftz binding sites on a Ecol\CAT reporter plasmid is studied.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
en::ftzEFE.hs
Name Synonyms
Secondary FlyBase IDs
    References (3)