FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmau\marinerTMos1
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General Information
Symbol
Dmau\mariner\TMos1
Species
D. mauritiana
Name
FlyBase ID
FBal0044747
Feature type
allele
Associated gene
Dmau\mariner\T
Associated Insertion(s)
Carried in Construct
Herm{M.ClaW}
Herm{M.ClaY}
P{M.Mos1.ry}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Garza et al., 1991)
Progenitor genotype
Carried in construct
Herm{M.ClaW}
Herm{M.ClaY}
P{M.Mos1.ry}
Cytology
Description

5kb fragment containing Dmau\mariner\T sequence flanked by approximately 3.5kb of D.simulans sequences and 0.2kb of D.simulans downstream sequences.

(Garza et al., 1991)
Allele components
Component
Use(s)
Encoded product / tool
Dmau\mariner\T
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Encodes a functional transposase.

      (Lidholm et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Used as source of transposase in demonstrating capability of Dmau\mariner to stably integrate into the zebrafish genome.

      (Fadool et al., 1998)

      Dmau\mariner\TMos1 can function as a transposase in the genome of D.melanogaster, promoting excision of the Dmau\mariner element from w::Dmau\wpch.tGa. The overall rates of Dmau\mariner excision are approximately sixfold greater than the rates in comparable strains of D.simulans. The Dmau\mariner element containing Dmau\mariner\TMos1 spontaneously integrated into the germline of D.melanogaster at high efficiency when injected into the pole plasm of D.melanogaster embryos.

      (Garza et al., 1991)

      Dmau\mariner\TMos1 functions as an autonomous Dmau\mariner element in D.simulans.

      (Medhora et al., 1991)

      Insertions into D.melanogaster (strain M3) and D.simulans (strain OX-2) are tested for transposase activity.

      (Nikitin and Woodruff, 1995)

      Carried in plasmid "pMos1" and transfected into the human parasite Leishmania major.

      (Gueiros-Filho and Beverley, 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dmau\mariner\TMos1
      Mos1
      (Hartl et al., 1997)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)