Contains approximately 5.2kb lab upstream sequences, all the lab transcribed region, except intron 1 which is replaced by a 280bp fragment derived from a partial cDNA clone, and approximately 2.5kb lab downstream sequences.
Comments on Models/Modifiers Based on Experimental Evidence
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Disease-implicated variant(s)
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Flies carrying labm2.5a together with interallelic combinations of lab mutations can emerge as adults with various head capsule defects, although some flies die at the pupal or occasionally the larval stage. The surviving adults show reduced fertility.