FB2026_02 , released June 18, 2026
Allele: Dmel\Abd-B::DfdHD.hs
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General Information
Symbol
Dmel\Abd-B::DfdHD.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0047980
Feature type
allele
Associated gene
Abd-B::Dfd
Associated Insertion(s)
Carried in Construct
P{Dfd/Abd-B}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Zhu and Kuziora, 1996)
Progenitor genotype
Carried in construct
P{Dfd/Abd-B}
Cytology
Description

Abd-B homeodomain amino acids 365-430 replaces the Dfd homeodomain, expressed from an Hsp70 promoter.

(Zhu and Kuziora, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Abd-B::Dfd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Transforms thoracic segments toward abdominal segment identity, as determined by the abdominal type denticles in the T2-T3 belts. The head fails to involute and mixed patches of thoracic and abdominal denticles appear in cephalic segments occasionally forming complete belts. 17% of cuticles exhibit a duplicated T1 beard in labial segments. Dorsal-lateral epidermis in abdominal and thoracic segments is transformed towards an A8 identity, causing ectopic filzkorper and perispiracular hairs.

      (Zhu and Kuziora, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Abd-B::DfdHD.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (1)