FB2026_02 , released June 18, 2026
Allele: Ecol\lacZDfd.4xE
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General Information
Symbol
Ecol\lacZDfd.4xE
Species
E. coli
Name
FlyBase ID
FBal0049899
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Dfd-lacZ.4xE}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(McGinnis et al., 1998, Gross and McGinnis, 1996, Zeng et al., 1994)
Progenitor genotype
Ecol\lacZhs43
(Gross and McGinnis, 1996)
Carried in construct
P{Dfd-lacZ.4xE}
Cytology
Description

4 copies of the 120bp fragment module E of the 2.7kb Dfd autoregulatory element (EAE).

(Pinsonneault et al., 1997)

lacZ reporter expression is driven by 4 copies of wild-type module E of the Dfd epidermal autoregulatory element (Dfd EAE) fused to an Hsp70 minimal promoter.

(Zeng et al., 1994)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 12 -- 17
      embryonic maxillary segment
      (Zeng et al., 1994)
      embryonic stage 13 -- 16
      embryonic maxillary segment
      (Pinsonneault et al., 1997)
      embryonic stage 13 -- 17
      epidermis of embryonic maxillary segment | posterior
      (Gross and McGinnis, 1996)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Dfd
      (Pinsonneault et al., 1997, Gross and McGinnis, 1996, Zeng et al., 1994)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZDfd.4xE
      lacZDfd.4xE
      Name Synonyms
      Secondary FlyBase IDs
        References (4)