FB2026_02 , released June 18, 2026
Allele: Dmel\nonARRM1-RNP2
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General Information
Symbol
Dmel\nonARRM1-RNP2
Species
D. melanogaster
Name
FlyBase ID
FBal0050209
Feature type
allele
Associated gene
Dmel\nonA
Associated Insertion(s)
Carried in Construct
P{RRM1-RNP2}
Key Links
Transgenic product class
missense_variant
(Stanewsky et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Stanewsky et al., 1996)
Mutagen
in vitro construct
(Stanewsky et al., 1996)
Progenitor genotype
Carried in construct
P{RRM1-RNP2}
Cytology
Description

Construct: Included within an 11kb XhoI-EcoRI fragment (compare to nonA+tXhR11). Amino acid 13 (a Y) in the RNP2 of RRM1 is replaced by an A.

(Stanewsky et al., 1996)
Allele components
Component
Use(s)
Encoded product / tool
nonA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In an otherwise nonA- background, viability is only 6-7% that of controls carrying P{132XhR11}. Survivors are generally disorientated and do not fly. Flies placed on an open table top stand in place and barely walk or move their legs. Males fall over and cannot get up. Fails to rescue the optomotor blindness associated with nonA mutants. Light-on/light-off transient-less phenotype caused by nonA- is not rescued. Males sing in a mutant manner, with wildly polycyclic pulses.

      (Stanewsky et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      nonARRM1-RNP2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)