FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\prdΔPB.hs
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General Information
Symbol
Dmel\prdΔPB.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0050281
Feature type
allele
Associated gene
Dmel\prd
Associated Insertion(s)
Carried in Construct
P{hs-prdΔPB}
Key Links
Transgenic product class
inframe_deletion
(Morrissey et al., 1991)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Morrissey et al., 1991)
Mutagen
in vitro construct
(Miskiewicz et al., 1996, Morrissey et al., 1991)
Progenitor genotype
Carried in construct
P{hs-prdΔPB}
Cytology
Description

An Hsp70 promoter drives expression of a prd cDNA with a deletion that removes 125 of the 128 amino acids of the paired-box domain.

(Morrissey et al., 1991)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
prd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heat shocked embryos show a range of cuticle phenotypes with variable substitution of naked cuticle by a reverse-polarity, mirror-symmetric pattern of denticles.

      (Morrissey et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "pHS-PRDΔPB", expressed in Schneider line 3 cells and tested for activation of the Ecol\CAT reporter gene to characterise the domains of ftz and prd.

      (Ananthan et al., 1993)

      Carried in plasmid "PrdΔHD", expressed in Schneider 3 cells and transcriptional activity of Ecol\CAT reporter construct is assayed.

      (Cai et al., 1994)

      Carried in plasmid and assayed in Schneider cells for ability to activate transcription from p3K'-TATA-CAT and pPB3-CAT.

      (Miskiewicz et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      prdΔPB.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (4)