FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\snSupS289N
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General Information
Symbol
Dmel\snSupS289N
Species
D. melanogaster
Name
FlyBase ID
FBal0050525
Feature type
allele
Associated gene
Dmel\sn
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Cant and Cooley, 1996)
Progenitor genotype
snS289N
(Cant and Cooley, 1996)
Cytology
Description

Amino acid replacement: S251F.

(Cant and Cooley, 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:7,984,595..7,984,595 [+]
Nucleotide change:

C7984595T

Reported nucleotide change:

C?T

Amino acid change:

S251F | sn-PA; S251F | sn-PB; S251F | sn-PE; S251F | sn-PG

Reported amino acid change:

S251F

Comment:

snSupS289N flies contain a S251F mutation in addition to the original S289N mutation of the snS289N strain.

(Cant and Cooley, 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Intermediate severity allele. Bristles are subtly bent, egg size is 80% wild type and flies are fertile. Nurse cells show defects in rapid cytoplasmic transport. Cytoplasmic actin bundles at the nurse cell membranes appear faint and disorganized.

      (Cant and Cooley, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      snSupS289N
      Name Synonyms
      Secondary FlyBase IDs
        References (1)