FB2026_02 , released June 18, 2026
Allele: Dmel\tRNA:Leu-CAA-1-1amber
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General Information
Symbol
Dmel\tRNA:Leu-CAA-1-1amber
Species
D. melanogaster
Name
FlyBase ID
FBal0050591
Feature type
allele
Associated gene
Dmel\tRNA:Leu-CAA-1-1
Associated Insertion(s)
Carried in Construct
P{DtLbSu+(amber)}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Washburn and O'Tousa, 1992, Garza et al., 1990)
Progenitor genotype
Carried in construct
P{DtLbSu+(amber)}
Cytology
Description

Contains tRNA:L3:49Fb coding sequences mutated at the anticodon to form an amber (UAG) nonsense suppressor.

(Garza et al., 1990)
Allele components
Component
Use(s)
Encoded product / tool
tRNA:Leu-CAA-1-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Weakly suppresses ninaE205UAG and does not detectably suppress ninaE1 or ninaE309UAG.

      (Washburn and O'Tousa, 1992)

      Males carrying tRNA:L3:49Fbamber show varying degrees of sterility. Sterile males produce only non-motile sperm.

      (Garza et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "pCopHygDtLbSu+(amber)", transfected into Schneider L2 cells and used to study the ability of tRNALeu suppressors to function in Drosophila.

      (Garza et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tRNA:L3:49Fbamber
      tRNA:Leu-CAA-1-1amber
      Name Synonyms
      Secondary FlyBase IDs
        References (2)