FB2026_02 , released June 18, 2026
Allele: Dmel\w::Dmauwpch.tGa
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General Information
Symbol
Dmel\w::Dmau\wpch.tGa
Species
D. melanogaster
Name
FlyBase ID
FBal0050759
Feature type
allele
Associated gene
w::Dmau\w
Associated Insertion(s)
Carried in Construct
P{M.wpch}
Also Known As
wpch
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lohe et al., 1996, Garza et al., 1991, Maruyama et al., 1991, Medhora et al., 1991)
Progenitor genotype
Dmau\wpch
(Garza et al., 1991)
Carried in construct
P{M.wpch}
Cytology
Description

BamHI fragment containing a Dmau\mariner element in the upstream region of Dmau\w replaces the homologous BamHI fragment spanning coordinate 1.0-4.0 in w+t11.7 (coordinates from FBrf0035956).

(Lohe et al., 1996)

Construct: 3.0kb BamHI fragment of w+t11.7 has been replaced by the corresponding 4.3kb BamHI fragment from Dmau\wpch containing the Dmau\wpch Dmau\mariner insertion.

(Garza et al., 1991)
Allele components
Component
Use(s)
Encoded product / tool
w::Dmau\w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: peach colored in the absence of Dmau\mariner transposase (in an otherwise w- background). Eye colour: mosaic peach/red (>200 spots per eye) in the presence of Dmau\mariner transposase (in an otherwise w- background).

      (Lohe et al., 2000)

      Eye colour: peach.

      (Lohe et al., 1996)

      w::Dmau\w transformed into D.melanogaster shows no evidence of somatic or germinal instability in the absence of other mariner elements.

      (Garza et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      In the presence of a copy of P{hsp70:Mos1}, the rate of germline excision of M{peach} from P{M{peach}wpch} is 16.9% (tested in D.melanogaster). Five out of seven insertions of P{hsp70:peach} result in a statistically significant reduction in the rate of germline excision of M{peach} from P{M{peach}wpch} caused by P{hsp70:Mos1} (tested in D.melanogaster). One out of three insertions of P{hsp70:DTBZ1} results in a statistically significant reduction in the rate of germline excision of M{peach} from P{M{peach}wpch} caused by P{hsp70:Mos1} (tested in D.melanogaster). In the presence of a copy of P{hsp26-Sgs3:Mos1}, the rate of germline excision of M{peach} from P{M{peach}wpch} is 19.9% (tested in D.melanogaster). Expression of Dtei\mariner\TDTBZ1.hs using heat shock results in a small but not significant reduction in the rate of germline excision of M{peach} from P{M{peach}wpch} caused by P{hsp26-Sgs3:Mos1} (tested in D.melanogaster). Expression of Hirr\Himar1\Ths.PL using heat shock does not result in a reduction in the rate of germline excision of M{peach} from P{M{peach}wpch} caused by P{hsp26-Sgs3:Mos1} (tested in D.melanogaster). P{hs-Hirr\Himar1\T.L} does not results in a reduction in the rate of germline excision of M{peach} from P{M{peach}wpch} caused by P{hsp70:Mos1} (tested in D.melanogaster).

      (De Aguiar and Hartl, 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Assayed in D.melanogaster.

      (Garza et al., 1991)

      Assayed in D.melanogaster. Used to determine the activity of a number of Dmau\mariner\T alleles.

      (Medhora et al., 1991)

      Assayed in D.melanogaster. Used to determine the activity of a number of Dmau\mariner\T alleles and a Dsim\mariner\T allele.

      (Maruyama et al., 1991)

      One copy of P{T42I}, P{E297K} or P{M1K} mutant Dmau\mariner\T reduces the amount of w::Dmau\wpch.tGa mosaicism. P{G292R} mutant transposase allows red pigmentation in several ommatidia. P{G292R}/P{hsp70:Mos1} allows an increase in w::Dmau\wpch.tGa mosaicism over the effect of P{G292R} alone but a reduction in mosaicism compared to a single copy of P{hsp70:Mos1} : negative complementation. P{E297K} also produces a small, but noticeable reduction in w::Dmau\wpch.tGa mosaicism in combination with P{hsp70:Mos1}. In the presence of a functional transposase the peach element is excised, restoring red pigment to the eyes. In the presence of P{hsp70:Mos1} the uniform peach colour changes to dark reddish-brown, even in the absence of heat shock, resulting in a mosaic red phenotype. Assayed in D.melanogaster.

      (Lohe et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      w::Dmau\wpch.tGa
      wpch
      (Maruyama et al., 1991, Medhora et al., 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)