Construct: Contains a stop codon that truncates the C-terminal 74 amino acids (539-613) including the PRD repeat (PR) and approximately 50 residues C-terminal to it.
Comments on Models/Modifiers Based on Experimental Evidence
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Disease-implicated variant(s)
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Can rescue prd function in an adult rescue assay, the degree of rescue forms a continuous distribution from fully mutant to fully wild type. The strongest line was able to rescue prd function as well as prdwt.